Heidrun Potschka Selected Research

Proteins (Proteins, Gene)

1/2021	Proteomic signature of the Dravet syndrome in the genetic Scn1a-A1783V mouse model.
1/2020	Regulation of Alzheimer's disease-associated proteins during epileptogenesis.
1/2020	Profiling the Expression of Endoplasmic Reticulum Stress Associated Heat Shock Proteins in Animal Epilepsy Models.
1/2017	Identification of brain regions predicting epileptogenesis by serial [18F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy.
11/2016	miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model.
6/2015	Glutamate-Mediated Down-Regulation of the Multidrug-Resistance Protein BCRP/ABCG2 in Porcine and Human Brain Capillaries.
10/2014	(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: evaluation in a rat epilepsy model.
4/2009	Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition.
2/2007	Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.
1/2005	Blood-brain barrier active efflux transporters: ATP-binding cassette gene family.

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Heidrun Potschka Research Topics

Disease

59	Epilepsy (Aura) 01/2024 - 09/2002
45	Seizures (Absence Seizure) 01/2023 - 04/2002
29	Status Epilepticus (Complex Partial Status Epilepticus) 01/2023 - 04/2002
19	Temporal Lobe Epilepsy 01/2021 - 01/2002
11	Drug Resistant Epilepsy 01/2024 - 04/2002
7	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2024 - 01/2021
5	Partial Epilepsies (Epilepsy, Partial) 01/2020 - 07/2002
4	Brain Diseases (Brain Disorder) 01/2024 - 02/2004
4	Body Weight (Weight, Body) 01/2023 - 01/2015
4	Central Nervous System Diseases (CNS Diseases) 05/2014 - 09/2009
3	Pain (Aches) 01/2023 - 06/2006
3	Mental Disorders (Mental Disorder) 12/2018 - 06/2006
3	Brain Ischemia (Cerebral Ischemia) 11/2016 - 10/2014
2	Ataxia (Dyssynergia) 12/2023 - 10/2004
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2008
2	Breast Neoplasms (Breast Cancer) 06/2015 - 01/2005
2	Inflammation (Inflammations) 10/2014 - 08/2008
2	Schizophrenia (Dementia Praecox) 09/2011 - 08/2005
1	Weight Gain 01/2023
1	Anhedonia 01/2021
1	Tuberous Sclerosis (Bourneville's Disease) 01/2021
1	Gliosis 01/2021
1	COVID-19 01/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021
1	Lennox Gastaut Syndrome 01/2021
1	Tremor (Tremors) 11/2020

Drug/Important Bio-Agent (IBA)

30	Anticonvulsants (Antiepileptic Drugs)IBA 08/2023 - 01/2002
19	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 09/2013 - 04/2002
11	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2004
10	Pilocarpine (Ocusert)FDA LinkGeneric 10/2019 - 04/2002
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2014
8	Phenobarbital (Luminal)FDA Link 01/2022 - 07/2002
8	Glutamic Acid (Glutamate)FDA Link 01/2021 - 06/2006
7	Kainic Acid (Kainate)IBA 01/2023 - 07/2002
6	Phenytoin (Dilantin)FDA LinkGeneric 10/2011 - 09/2002
5	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2022 - 05/2008
5	Levetiracetam (Keppra)FDA LinkGeneric 01/2022 - 04/2002
5	Peptides (Polypeptides)IBA 03/2014 - 09/2011
4	LigandsIBA 01/2021 - 03/2010
4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2014 - 04/2003
4	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 09/2011 - 07/2007
3	CorticosteroneIBA 01/2023 - 01/2018
3	SaccharinIBA 01/2023 - 01/2019
3	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2022 - 02/2010
3	4- (2'- methoxyphenyl)- 1- (2'- (N- 2'- pyridinyl)- p- (18F)fluorobenzamido )ethylpiperazineIBA 01/2021 - 10/2018
3	AWD 131-138IBA 11/2020 - 10/2004
2	Voltage-Gated Sodium ChannelsIBA 01/2024 - 12/2023
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2023 - 10/2018
2	MicroRNAs (MicroRNA)IBA 01/2023 - 11/2016
2	CannabidiolIBA 12/2022 - 01/2021
2	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 08/2015
2	5-HT1A Serotonin ReceptorIBA 01/2021 - 10/2018
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2020 - 01/2019
2	perampanelIBA 01/2019 - 04/2016
2	Deoxyglucose (2 Deoxy D glucose)IBA 12/2018 - 10/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2015 - 01/2010
2	Neuropeptide YIBA 10/2014 - 01/2004
2	Neuroprotective AgentsIBA 10/2014 - 09/2011
2	Lacosamide FDA Link 07/2013 - 11/2006
2	Lamotrigine (Lamictal)FDA LinkGeneric 09/2012 - 07/2002
2	Erythropoietin FDA Link 12/2011 - 10/2011
2	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 09/2010 - 02/2010
2	polysialic acidIBA 06/2010 - 04/2008
2	PlasticsIBA 04/2008 - 07/2007
2	polysialyl neural cell adhesion moleculeIBA 04/2008 - 07/2007
2	Diazepam (Valium)FDA LinkGeneric 06/2003 - 10/2002
1	Messenger RNA (mRNA)IBA 01/2024
1	lorcaserinIBA 12/2023
1	clemizoleIBA 12/2023
1	atalurenIBA 12/2023
1	Antidepressive Agents (Antidepressants)IBA 01/2023
1	Imipramine (Janimine)FDA LinkGeneric 01/2023
1	Drug CombinationsIBA 12/2022
1	CannabinoidsIBA 12/2022
1	Sodium Channels (Sodium Channel)IBA 11/2022
1	firocoxibIBA 01/2022
1	Pregabalin (Lyrica)FDA Link 01/2022
1	Ion Channels (Ion Channel)IBA 01/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021
1	gamma-Aminobutyric Acid (GABA)IBA 01/2021
1	FenfluramineIBA 01/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021
1	ProteomeIBA 01/2021
1	Everolimus FDA Link 01/2021
1	Investigational DrugsIBA 01/2021
1	TOR Serine-Threonine KinasesIBA 01/2021
1	Anti-Anxiety Agents (Anxiolytics)IBA 11/2020
1	Butyric Acid (Butanoic Acid)IBA 11/2020
1	Tramadol (K315)FDA LinkGeneric 02/2020

Therapy/Procedure

12	Therapeutics 01/2024 - 08/2005
2	Electrodes (Electrode) 01/2023 - 02/2014
2	Ketogenic Diet 12/2021 - 01/2021
2	Drug Therapy (Chemotherapy) 01/2020 - 04/2009
2	Implanted Electrodes 08/2013 - 10/2011
1	Analgesia 01/2023
1	Neurosurgical Procedures 01/2023
1	Craniotomy 01/2023
1	Operative Surgical Procedures 01/2023
1	Laparotomy 01/2022
1	Euthanasia (Mercy Killing) 02/2020